BCL9

Across TCGA patient cohorts, BCL9 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,131 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BCL9-associated proteins across cancer lineages are BCL9_S917, DHX9, and RBBP5. Each is linked with BCL9 in more than 7 cancer types. Because this analysis shows association rather than direction, both BCL9-to-partner and partner-to-BCL9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL9 versus BCL9_S917 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL9→partner) and Y-score (partner→BCL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BCL9_S917 →	+0.672	+0.846	.001	.003	3	8
COAD	DHX9 →	+0.212	+0.890	<.001	<.001	3	7
GBM	RBBP5 →	+0.250	+0.394	.002	.005	3	6
PDAC	RO60 →	+0.252	+0.410	<.001	<.001	3	6
LSCC	BCL9_S278 →	+0.607	+0.594	<.001	<.001	3	6
LSCC	C1orf35 →	+0.406	+0.576	.002	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,131 associations by consensus.

BCL9 vs BCL9_S917 — HNSC

Explore this scatter interactively →