BCL7A

Across TCGA patient cohorts, BCL7A mutation is significantly associated with the RNA expression of many other genes, with 605 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL7A-associated genes across cancer lineages are CDKN2AIPNLP2, LINC02291, and RPL21P50. Each is linked with BCL7A in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL7A-to-partner and partner-to-BCL7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDKN2AIPNLP2 grouped by BCL7A-low versus BCL7A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL7A→partner) and Y-score (partner→BCL7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	CDKN2AIPNLP2 →	+0.110	+5.306	<.001	.006	3	1
CESC	LINC02291 →	+0.021	+5.306	<.001	.006	3	1
CESC	RPL21P50 →	+0.094	+5.010	<.001	.009	3	1
CESC	PCDH9-AS2 →	+0.057	+5.969	<.001	.002	3	1
CESC	SS18L2P1 →	+0.198	+5.306	<.001	.006	3	1
COAD	ULK4P3 →	+0.098	+4.510	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 605 associations by consensus.

CDKN2AIPNLP2 by BCL7A expression — CESC

Explore this box plot interactively →