BCL6B

Across TCGA cell cohorts, BCL6B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,615 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BCL6B-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of type I interferon production, and Response to type I interferon. Each is linked with BCL6B in more than 6 cancer types. Because this analysis shows association rather than direction, both BCL6B-to-partner and partner-to-BCL6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by BCL6B-low versus BCL6B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL6B→partner) and Y-score (partner→BCL6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of myoblast fusion →	+0.077	+0.056	.009	.008	3	7
KIDNEY	Regulation of type I interferon production →	+0.038	+0.052	.007	.003	3	6
KIDNEY	Response to type I interferon →	+0.075	+0.054	.002	.001	3	6
KIDNEY	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.080	+0.077	.001	.002	3	5
URINARY_TRACT	RNA splicing, via transesterification reactions →	+0.060	+0.096	<.001	.004	3	5
BONE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.061	+0.480	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,615 associations by consensus.

Negative regulation of myoblast fusion by BCL6B expression — KIDNEY

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