BCL2L2

Across TCGA patient cohorts, BCL2L2 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL2L2-associated genes across cancer lineages are p27_pT198 and JNK2. Each is linked with BCL2L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL2L2-to-partner and partner-to-BCL2L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p27_pT198 grouped by BCL2L2-low versus BCL2L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L2→partner) and Y-score (partner→BCL2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.157	+3.169	.007	.020	3	1
UCEC	JNK2 →	+0.278	+3.169	.010	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

p27_pT198 by BCL2L2 expression — UCEC

Explore this box plot interactively →