BCL2L12

Across TCGA cell cohorts, BCL2L12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,531 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BCL2L12-associated GO terms across cancer lineages are Double-strand break repair via break-induced replication, Meiotic sister chromatid cohesion, centromeric, and DNA replication. Each is linked with BCL2L12 in more than 16 cancer types. Because this analysis shows association rather than direction, both BCL2L12-to-partner and partner-to-BCL2L12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via break-induced replication grouped by BCL2L12-low versus BCL2L12-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L12→partner) and Y-score (partner→BCL2L12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Double-strand break repair via break-induced replication →	+0.277	+1.182	.001	<.001	3	17
BONE	Meiotic sister chromatid cohesion, centromeric →	+0.154	+1.126	.003	.006	3	16
OESOPHAGUS	DNA replication →	+0.133	+1.041	<.001	<.001	3	16
OESOPHAGUS	DNA-templated DNA replication →	+0.143	+1.041	<.001	<.001	3	16
BONE	DNA replication initiation →	+0.200	+1.307	.004	.001	2	17
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.235	+1.163	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,531 associations by consensus.

Double-strand break repair via break-induced replication by BCL2L12 expression — BONE

Explore this box plot interactively →