BCL2L11

Across TCGA patient cohorts, BCL2L11 protein abundance is significantly associated with the RNA expression of many other genes, with 4,613 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCL2L11-associated genes across cancer lineages are MAST4, NRP1, and DDR2. Each is linked with BCL2L11 in more than 3 cancer types. Because this analysis shows association rather than direction, both BCL2L11-to-partner and partner-to-BCL2L11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL2L11 versus MAST4 in OV, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L11→partner) and Y-score (partner→BCL2L11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAST4 →	-0.825	-0.340	.007	<.001	3	4
OV	NRP1 →	-0.946	-0.362	<.001	.003	3	4
OV	DDR2 →	-0.938	-0.261	.001	.006	3	3
UCEC	PDLIM5 →	-0.716	-0.657	<.001	.002	3	3
BRCA	ERO1A →	-0.978	-0.511	<.001	<.001	3	3
PDAC	LIMCH1 →	-1.299	-0.969	.004	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,613 associations by consensus.

BCL2L11 vs MAST4 — OV

Explore this scatter interactively →