BCL2L11

Across TCGA patient cohorts, BCL2L11 mutation is significantly associated with the RNA expression of many other genes, with 3,023 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL2L11-associated genes across cancer lineages are RN7SL97P, RN7SKP154, and COX15. Each is linked with BCL2L11 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL2L11-to-partner and partner-to-BCL2L11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL97P grouped by BCL2L11-low versus BCL2L11-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L11→partner) and Y-score (partner→BCL2L11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL97P →	+0.230	+5.144	<.001	.003	3	2
CESC	RN7SKP154 →	+0.109	+4.812	<.001	.006	3	2
UCEC	COX15 →	+0.403	+3.095	<.001	<.001	3	2
UCEC	EME1 →	+0.534	+2.457	<.001	.001	3	2
UCEC	BUB1B →	+0.608	+3.721	.003	<.001	3	2
UCEC	FEN1 →	+0.555	+3.917	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,023 associations by consensus.

RN7SL97P by BCL2L11 expression — CESC

Explore this box plot interactively →