BCL2L11

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BCL2L11 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BCL2L11-associated genes across cancer lineages are AVP. Each is linked with BCL2L11 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL2L11-to-partner and partner-to-BCL2L11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by BCL2L11-low versus BCL2L11-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L11→partner) and Y-score (partner→BCL2L11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaAVP →+0.031+5.209<.001.00531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

AVP by BCL2L11 expression — BLOOD_Lymphoma

Box plot of AVP in BCL2L11-low vs BCL2L11-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration