BCL2L10

Across TCGA cell cohorts, BCL2L10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,444 significant associations in total. CNS shows the largest number of these associations.

The most reproducible BCL2L10-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Viral process, and Cytoplasmic translation. Each is linked with BCL2L10 in more than 7 cancer types. Because this analysis shows association rather than direction, both BCL2L10-to-partner and partner-to-BCL2L10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by BCL2L10-low versus BCL2L10-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L10→partner) and Y-score (partner→BCL2L10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.074	+0.201	<.001	.009	3	8
BLOOD_Lymphoma	Viral process →	+0.045	+0.445	<.001	.001	2	8
BLOOD_Lymphoma	Cytoplasmic translation →	+0.073	+0.363	<.001	.003	3	7
URINARY_TRACT	Positive regulation of canonical NF-kappaB signal transduction →	+0.058	+1.066	<.001	.008	3	7
SOFT_TISSUE	Regulation of cellular response to heat →	+0.093	+0.309	<.001	.003	3	7
LUNG_NSCLC_LUAD	Negative regulation of myoblast fusion →	+0.044	+0.425	.001	.008	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,444 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by BCL2L10 expression — SOFT_TISSUE

Explore this box plot interactively →