BCL2L10

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BCL2L10 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BCL2L10-associated genes across cancer lineages are GKN1. Each is linked with BCL2L10 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL2L10-to-partner and partner-to-BCL2L10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GKN1 grouped by BCL2L10-low versus BCL2L10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L10→partner) and Y-score (partner→BCL2L10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaGKN1 →+0.078+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GKN1 by BCL2L10 expression — BLOOD_Leukemia

Box plot of GKN1 in BCL2L10-low vs BCL2L10-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration