BCL2L1

Across TCGA cell cohorts, BCL2L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,285 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BCL2L1-associated GO terms across cancer lineages are Protein localization to plasma membrane, Process utilizing autophagic mechanism, and Autophagy. Each is linked with BCL2L1 in more than 12 cancer types. Because this analysis shows association rather than direction, both BCL2L1-to-partner and partner-to-BCL2L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to plasma membrane grouped by BCL2L1-low versus BCL2L1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L1→partner) and Y-score (partner→BCL2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Protein localization to plasma membrane →	+0.076	+0.837	<.001	<.001	3	13
LARGE_INTESTINE	Process utilizing autophagic mechanism →	+0.054	+1.070	<.001	<.001	3	13
LARGE_INTESTINE	Autophagy →	+0.054	+1.070	<.001	<.001	3	13
LARGE_INTESTINE	ERBB signaling pathway →	+0.088	+1.776	<.001	<.001	3	12
KIDNEY	Cellular response to abiotic stimulus →	+0.046	+1.242	.007	.002	3	12
LARGE_INTESTINE	Rho protein signal transduction →	+0.146	+1.427	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,285 associations by consensus.

Protein localization to plasma membrane by BCL2L1 expression — SKIN

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