BCL2A1

Across TCGA patient cohorts, BCL2A1 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL2A1-associated genes across cancer lineages are c-Jun_pS73, SF2, and Caspase-8. Each is linked with BCL2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL2A1-to-partner and partner-to-BCL2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, c-Jun_pS73 grouped by BCL2A1-low versus BCL2A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2A1→partner) and Y-score (partner→BCL2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	c-Jun_pS73 →	-0.165	-2.990	.047	.036	3	1
UCEC	SF2 →	+0.123	+3.009	.031	.019	2	1
UCEC	Caspase-8 →	-0.319	-3.321	.015	.010	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

c-Jun_pS73 by BCL2A1 expression — UCEC

Explore this box plot interactively →