BCL2A1

Across TCGA cell cohorts, BCL2A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,176 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BCL2A1-associated GO terms across cancer lineages are Intracellular receptor signaling pathway, Zymogen activation, and Regulation of extrinsic apoptotic signaling pathway. Each is linked with BCL2A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both BCL2A1-to-partner and partner-to-BCL2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular receptor signaling pathway grouped by BCL2A1-low versus BCL2A1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2A1→partner) and Y-score (partner→BCL2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Intracellular receptor signaling pathway →	+0.043	+1.230	.001	.003	3	8
SOFT_TISSUE	Zymogen activation →	+0.270	+2.099	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of extrinsic apoptotic signaling pathway →	+0.079	+1.073	<.001	.004	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of lymphocyte activation →	+0.077	+1.126	<.001	<.001	3	8
KIDNEY	T-helper 17 cell lineage commitment →	+0.185	+1.695	<.001	<.001	3	8
SOFT_TISSUE	Fibrinolysis →	+0.828	+1.580	.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,176 associations by consensus.

Intracellular receptor signaling pathway by BCL2A1 expression — SOFT_TISSUE

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