BCL11B

Across TCGA patient cohorts, BCL11B protein abundance is significantly associated with the RNA expression of many other genes, with 6,163 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCL11B-associated genes across cancer lineages are GNAI2, VASP, and CDC42EP3. Each is linked with BCL11B in more than 2 cancer types. Because this analysis shows association rather than direction, both BCL11B-to-partner and partner-to-BCL11B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL11B versus GNAI2 in GBM, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL11B→partner) and Y-score (partner→BCL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GNAI2 →	-0.332	-0.829	.001	.001	3	3
GBM	VASP →	-0.472	-0.796	.009	<.001	3	3
LSCC	CDC42EP3 →	-0.729	-0.656	<.001	<.001	3	3
LSCC	ICA1 →	-0.867	-0.525	<.001	<.001	3	3
LSCC	ZNF706 →	+0.610	+0.495	<.001	<.001	3	3
COAD	NOP16 →	+0.424	+0.819	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,163 associations by consensus.

BCL11B vs GNAI2 — GBM

Explore this scatter interactively →