BCL11B

Across TCGA cell cohorts, BCL11B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,887 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BCL11B-associated GO terms across cancer lineages are Regulation of cytoplasmic translation, Regulation of stem cell differentiation, and Cellular response to fatty acid. Each is linked with BCL11B in more than 7 cancer types. Because this analysis shows association rather than direction, both BCL11B-to-partner and partner-to-BCL11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic translation grouped by BCL11B-low versus BCL11B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL11B→partner) and Y-score (partner→BCL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cytoplasmic translation →	+0.083	+2.722	<.001	<.001	3	8
URINARY_TRACT	Regulation of stem cell differentiation →	+0.080	+0.494	.001	.001	3	8
URINARY_TRACT	Cellular response to fatty acid →	+0.149	+0.696	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Calcium ion transport →	-0.063	-1.002	.004	.005	3	8
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.080	+1.433	.002	.003	3	8
BONE	Epigenetic regulation of gene expression →	+0.097	+3.068	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,887 associations by consensus.

Regulation of cytoplasmic translation by BCL11B expression — BONE

Explore this box plot interactively →