BCL10

Across TCGA cell cohorts, BCL10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,386 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BCL10-associated GO terms across cancer lineages are Regulation of lymphotoxin A production, Positive regulation of lymphotoxin A production, and Regulation of mast cell cytokine production. Each is linked with BCL10 in more than 18 cancer types. Because this analysis shows association rather than direction, both BCL10-to-partner and partner-to-BCL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lymphotoxin A production grouped by BCL10-low versus BCL10-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL10→partner) and Y-score (partner→BCL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of lymphotoxin A production →	+1.177	+1.134	.001	<.001	3	19
STOMACH	Positive regulation of lymphotoxin A production →	+1.177	+1.134	.001	<.001	3	19
BREAST	Regulation of mast cell cytokine production →	+1.247	+1.003	<.001	<.001	3	18
BREAST	Positive regulation of mast cell cytokine production →	+1.247	+1.003	<.001	<.001	3	18
SOFT_TISSUE	Cellular response to mechanical stimulus →	+0.121	+1.023	<.001	<.001	3	14
BONE	Zinc ion import into Golgi lumen →	+0.108	+0.830	.003	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,386 associations by consensus.

Regulation of lymphotoxin A production by BCL10 expression — STOMACH

Explore this box plot interactively →