BCKDK

Across TCGA patient cohorts, BCKDK protein abundance is significantly associated with the protein abundance of many other proteins, with 12,369 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BCKDK-associated proteins across cancer lineages are DBT, DNAJA3, and BCKDK_S31. Each is linked with BCKDK in more than 9 cancer types. Because this analysis shows association rather than direction, both BCKDK-to-partner and partner-to-BCKDK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCKDK versus DBT in UCEC, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCKDK→partner) and Y-score (partner→BCKDK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DBT →	+0.545	+0.373	<.001	<.001	3	9
OV	DNAJA3 →	+0.423	+0.335	<.001	<.001	3	9
BRCA	BCKDK_S31 →	+1.314	+0.599	<.001	<.001	3	8
OV	TUFM →	+0.368	+0.307	.004	<.001	1	10
GBM	HARS2 →	+0.312	+0.336	<.001	<.001	3	8
BRCA	HMGCL →	+0.537	+0.445	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,369 associations by consensus.

BCKDK vs DBT — UCEC

Explore this scatter interactively →