Across TCGA patient cohorts, BCKDHA RNA expression is significantly associated with the go_rna of many other GO terms, with 7,143 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible BCKDHA-associated GO terms across cancer lineages are Obsolete selective autophagy, Branched-chain amino acid catabolic process, and Regulation of protein sumoylation. Each is linked with BCKDHA in more than 27 cancer types. Because this analysis shows association rather than direction, both BCKDHA-to-partner and partner-to-BCKDHA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCKDHA→partner) and Y-score (partner→BCKDHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Obsolete selective autophagy →	+0.047	+0.743	<.001	<.001	3	28
ACC	Branched-chain amino acid catabolic process →	+0.064	+1.503	<.001	<.001	3	27
TGCT	Regulation of protein sumoylation →	+0.067	+0.682	<.001	<.001	3	27
DLBC	Protein demethylation →	+0.101	+0.815	<.001	<.001	3	26
DLBC	Negative regulation of telomere capping →	+0.071	+0.910	<.001	<.001	3	26
DLBC	Negative regulation of protein sumoylation →	+0.092	+1.049	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,143 associations by consensus.

Exploration

BCKDHA survival (RNA) · tumor vs normal (RNA) · all BCKDHA data types