BCKDHA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BCKDHA protein abundance is significantly associated with the protein abundance of many other proteins, with 1,650 significant associations in total. CNS shows the largest number of these associations.

The most reproducible BCKDHA-associated proteins across cancer lineages are BCKDHB, NIPSNAP2, and HMGCL. Each is linked with BCKDHA in more than 7 cancer types. Because this analysis shows association rather than direction, both BCKDHA-to-partner and partner-to-BCKDHA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCKDHA versus BCKDHB in PANCREAS, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCKDHA→partner) and Y-score (partner→BCKDHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASBCKDHB →+1.315+1.256<.001<.00138
STOMACHNIPSNAP2 →+1.798+1.243.001.00938
PANCREASHMGCL →+1.124+0.707.001<.00138
STOMACHHSD17B4 →+1.527+1.157.001.00537
STOMACHNIPSNAP1 →+1.712+1.300.008.00737
LARGE_INTESTINENAP1L1 →-1.425-0.784.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,650 associations by consensus.

BCKDHA vs BCKDHB — PANCREAS

Per-sample scatter of BCKDHA vs BCKDHB in PANCREAS (Pearson r = 0.71).

Explore this scatter interactively →

Exploration