BCHE

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BCHE protein abundance is significantly associated with the RNA expression of many other genes, with 12,410 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BCHE-associated genes across cancer lineages are CNRIP1, MYCT1, and RHOJ. Each is linked with BCHE in more than 6 cancer types. Because this analysis shows association rather than direction, both BCHE-to-partner and partner-to-BCHE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCHE versus CNRIP1 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCHE→partner) and Y-score (partner→BCHE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACNRIP1 →+0.962+0.757<.001<.00137
UCECMYCT1 →+0.832+0.640<.001<.00137
OVRHOJ →+0.921+0.805<.001<.00137
BRCAADGRL4 →+0.837+0.583<.001<.00137
BRCAMSRB3 →+1.339+0.697<.001<.00137
OVABCC9 →+1.185+0.651<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,410 associations by consensus.

BCHE vs CNRIP1 — BRCA

Per-sample scatter of BCHE vs CNRIP1 in BRCA (Pearson r = 0.43).

Explore this scatter interactively →

Exploration