Across TCGA pan-cancer cohorts, BCDIN3D mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated BCDIN3D data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher BCDIN3D mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BCDIN3D expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, UCEC, and GBM are the cancer types where BCDIN3D mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.907	0.405	.001	11	view →
UCEC	DFS	Median	All	1.000	0.840	.019	6	view →
GBM	DFS	Tertile	All	0.478	0.258	.020	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: BCDIN3D tumor-vs-normal RNA expression · all BCDIN3D data types