BCCIP

Across TCGA pan-cancer cohorts, BCCIP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BCCIP data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher BCCIP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BCCIP expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, GBM, and COAD are the cancer types where BCCIP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	II,III,IV	0.914	0.476	<.001	30	view →
GBM	DFS	Quartile	All	0.478	0.288	.008	12	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
UCEC	DFS	Median	II,III,IV	0.882	0.518	.030	4	view →
HNSC	DFS	Quartile	All	0.783	0.556	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BCCIP–LSCC (DFS)

Open the LSCC breakdown →