BCAT2

Across TCGA patient cohorts, BCAT2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,573 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BCAT2-associated genes across cancer lineages are CCNB1, FEN1, and EXO1. Each is linked with BCAT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both BCAT2-to-partner and partner-to-BCAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCAT2 versus CCNB1 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAT2→partner) and Y-score (partner→BCAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCNB1 →	-0.925	-0.692	<.001	<.001	3	4
BRCA	FEN1 →	-0.818	-0.526	<.001	.002	3	4
BRCA	EXO1 →	-1.024	-0.565	<.001	<.001	3	4
COAD	H2AX →	-0.802	-0.350	.001	.007	3	4
BRCA	UBE2T →	-1.016	-0.563	<.001	<.001	3	4
BRCA	BIRC5 →	-0.997	-0.558	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,573 associations by consensus.

BCAT2 vs CCNB1 — BRCA

Explore this scatter interactively →