BCAT2

Across TCGA cell cohorts, BCAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,507 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BCAT2-associated GO terms across cancer lineages are Isoleucine metabolic process, L-isoleucine catabolic process, and Positive regulation of T-helper 17 cell lineage commitment. Each is linked with BCAT2 in more than 10 cancer types. Because this analysis shows association rather than direction, both BCAT2-to-partner and partner-to-BCAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Isoleucine metabolic process grouped by BCAT2-low versus BCAT2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAT2→partner) and Y-score (partner→BCAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Isoleucine metabolic process →	+0.185	+0.977	<.001	<.001	3	11
BREAST	L-isoleucine catabolic process →	+0.185	+0.977	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Positive regulation of T-helper 17 cell lineage commitment →	+0.199	+0.947	<.001	<.001	3	11
BONE	Nucleosome disassembly →	+0.196	+0.865	.001	.002	3	10
STOMACH	mRNA alternative polyadenylation →	+0.108	+1.107	<.001	.004	3	10
UPPER_AERODIGESTIVE_TRACT	RNA catabolic process →	+0.051	+0.607	.001	.007	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,507 associations by consensus.

Isoleucine metabolic process by BCAT2 expression — BREAST

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