BCAS4

Across TCGA patient cohorts, BCAS4 mutation is significantly associated with the RNA expression of many other genes, with 2,532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCAS4-associated genes across cancer lineages are MIR7976, PLCE1P1, and MIR4769. Each is linked with BCAS4 in more than 2 cancer types. Because this analysis shows association rather than direction, both BCAS4-to-partner and partner-to-BCAS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7976 grouped by BCAS4-low versus BCAS4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAS4→partner) and Y-score (partner→BCAS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7976 →	+0.416	+2.190	<.001	.009	3	3
BRCA	PLCE1P1 →	+0.118	+7.731	<.001	.009	3	2
CESC	MIR4769 →	+0.503	+6.164	<.001	<.001	3	2
BRCA	RNU6-113P →	+0.311	+8.055	<.001	.007	3	2
SKCM	LINC01670 →	+0.061	+3.310	<.001	.008	3	2
COAD	BCAR1P2 →	+0.339	+5.173	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,532 associations by consensus.

MIR7976 by BCAS4 expression — UCEC

Explore this box plot interactively →