BCAS3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BCAS3 mutation is significantly associated with the RNA expression of many other genes, with 1,040 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BCAS3-associated genes across cancer lineages are KRT71, C16orf90, and LILRA1. Each is linked with BCAS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCAS3-to-partner and partner-to-BCAS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT71 grouped by BCAS3-low versus BCAS3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAS3→partner) and Y-score (partner→BCAS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEKRT71 →+0.006+5.369<.001.00432
LUNG_NSCLC_LUADC16orf90 →+0.027+3.188<.001.00432
SOFT_TISSUELILRA1 →+0.113+4.930<.001.00831
SOFT_TISSUEZAN →+0.006+5.369<.001.00431
SOFT_TISSUEDTHD1 →+0.006+4.930<.001.00831
SOFT_TISSUESLC22A6 →+0.025+4.930<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,040 associations by consensus.

KRT71 by BCAS3 expression — SOFT_TISSUE

Box plot of KRT71 in BCAS3-low vs BCAS3-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration