BCAS1

Across TCGA pan-cancer cohorts, BCAS1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated BCAS1 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher BCAS1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated BCAS1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, LSCC, and HNSC are the cancer types where BCAS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.759	0.450	.003	29	view →
LSCC	OS	Quartile	All	0.630	0.897	.029	11	view →
HNSC	DFS	Median	All	0.854	0.355	.030	6	view →
LUAD	DFS	Median	All	0.646	0.842	.016	4	view →
UCEC	DFS	Median	All	0.953	0.848	.029	2	view →
GBM	OS	Median	All	0.402	0.613	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

BCAS1–PDAC (OS)

Open the PDAC breakdown →