BCAS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BCAS1 mutation is significantly associated with the RNA expression of many other genes, with 2,890 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCAS1-associated genes across cancer lineages are MIR4752, MIR7-3, and RCCD1-AS1. Each is linked with BCAS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BCAS1-to-partner and partner-to-BCAS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4752 grouped by BCAS1-low versus BCAS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAS1→partner) and Y-score (partner→BCAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR4752 →+0.077+4.311<.001.00234
LUSCMIR7-3 →+0.259+4.517<.001.00433
SKCMRCCD1-AS1 →+0.250+3.077<.001<.00133
LUSCTMEM225 →+0.213+4.454<.001<.00133
LUSCRN7SL454P →+0.204+3.434.004.00133
LUSCNFILZ →+0.257+3.969<.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,890 associations by consensus.

MIR4752 by BCAS1 expression — UCEC

Box plot of MIR4752 in BCAS1-low vs BCAS1-high samples in UCEC.

Explore this box plot interactively →

Exploration