BCAS1

Across TCGA cell cohorts, BCAS1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BCAS1-associated genes across cancer lineages are CXorf51A, GZMH, and RFPL3. Each is linked with BCAS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCAS1-to-partner and partner-to-BCAS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXorf51A grouped by BCAS1-low versus BCAS1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAS1→partner) and Y-score (partner→BCAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CXorf51A →	+0.092	+5.169	<.001	.005	3	1
CNS	GZMH →	+0.015	+3.772	<.001	.008	3	1
CNS	RFPL3 →	+0.129	+2.715	<.001	.007	3	1
LUNG_NSCLC_LUAD	MMP27 →	+0.029	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR13C4 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	CCL19 →	+0.080	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CXorf51A by BCAS1 expression — BREAST

Explore this box plot interactively →