BCAS1

Across TCGA cell cohorts, BCAS1 mutation is significantly associated with the mutation status of many other genes, with 1,502 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BCAS1-associated genes across cancer lineages are LZTS2, GABRB1, and PI16. Each is linked with BCAS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BCAS1-to-partner and partner-to-BCAS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LZTS2 grouped by BCAS1-low versus BCAS1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAS1→partner) and Y-score (partner→BCAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	LZTS2 →	+4.014	+4.969	.008	.008	1	4
BREAST	GABRB1 →	+4.297	+4.857	.009	.009	1	3
BREAST	PI16 →	+5.297	+5.297	.004	.004	1	3
BREAST	ELFN2 →	+4.297	+4.857	.009	.009	1	3
LUNG_NSCLC_LUSC	APBA1 →	+3.263	+3.938	.002	.002	1	3
LUNG_NSCLC_LUSC	AIFM3 →	+4.263	+4.263	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,502 associations by consensus.

LZTS2 by BCAS1 expression — BLOOD_Lymphoma

Explore this box plot interactively →