Across TCGA patient cohorts, BCAP31 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCAP31-associated genes across cancer lineages are ATM, Bax, and eEF2. Each is linked with BCAP31 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCAP31-to-partner and partner-to-BCAP31 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAP31→partner) and Y-score (partner→BCAP31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.690	-2.906	<.001	.001	3	2
UCEC	Bax →	+0.334	+2.459	.001	.018	3	2
UCEC	eEF2 →	+0.366	+3.169	.015	.018	3	1
UCEC	ERK2 →	+0.240	+2.584	.003	.010	3	1
UCEC	INPP4B →	-0.277	-2.321	.043	.034	3	1
UCEC	JNK2 →	+0.267	+3.026	.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

BCAP31 survival (RNA) · tumor vs normal (RNA) · all BCAP31 data types