BCAN

Across TCGA pan-cancer cohorts, BCAN Mutation is linked to patient survival in 11 of 34 cancer types, making it a survival-associated BCAN data layer compared with 23 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher BCAN Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BCAN expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KIRP, OV, and UCEC are the cancer types where BCAN Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.574	0.885	<.001	30	view →
OV	OS	Median	II,III,IV	0.335	0.693	.011	30	view →
UCEC	DFS	Median	All	0.974	0.618	.002	28	view →
LIHC	OS	Median	All	0.051	0.775	<.001	24	view →
SKCM	OS	Median	All	0.353	0.797	<.001	13	view →
CHOL	DFS	Median	All	0.121	0.495	.024	6	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →
SARC	DFS	Median	All	0.107	0.613	<.001	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
BRCA	OS	Median	All	0.166	0.579	.040	4	view →
MESO	OS	Median	All	0.169	0.556	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

BCAN–KIRP (OS)

Open the KIRP breakdown →