BBX

Across TCGA patient cohorts, BBX RNA expression is significantly associated with the protein abundance of many other proteins, with 11,825 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BBX-associated proteins across cancer lineages are BBX_S844, RAB3D, and FXR1. Each is linked with BBX in more than 6 cancer types. Because this analysis shows association rather than direction, both BBX-to-partner and partner-to-BBX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBX versus BBX_S844 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BBX→partner) and Y-score (partner→BBX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BBX_S844 →	+0.381	+0.412	<.001	<.001	3	7
HNSC	RAB3D →	-0.629	-0.689	<.001	<.001	3	5
LSCC	FXR1 →	+0.338	+0.400	<.001	<.001	3	5
LSCC	LPGAT1 →	+0.292	+0.481	.008	.001	3	4
OV	MRPS9 →	-0.265	-0.570	.009	.002	3	4
OV	SLIRP →	-0.577	-0.694	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,825 associations by consensus.

BBX vs BBX_S844 — GBM

Explore this scatter interactively →