BBX

Across TCGA cell cohorts, BBX RNA expression is significantly associated with the go_rna of many other GO terms, with 5,080 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BBX-associated GO terms across cancer lineages are Regulation of organelle assembly, Negative regulation of organelle assembly, and Host-mediated perturbation of viral process. Each is linked with BBX in more than 15 cancer types. Because this analysis shows association rather than direction, both BBX-to-partner and partner-to-BBX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by BBX-low versus BBX-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BBX→partner) and Y-score (partner→BBX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of organelle assembly →	+0.051	+1.341	.001	.004	3	16
BONE	Negative regulation of organelle assembly →	+0.074	+1.003	.001	.003	3	16
STOMACH	Host-mediated perturbation of viral process →	+0.098	+1.309	<.001	.003	3	16
KIDNEY	Protein localization to chromosome, telomeric region →	+0.096	+1.251	.001	.001	3	15
STOMACH	Regulation of intracellular transport →	+0.061	+1.057	.001	<.001	3	15
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.112	+0.774	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,080 associations by consensus.

Regulation of organelle assembly by BBX expression — OESOPHAGUS

Explore this box plot interactively →