BBS7

Across TCGA cell cohorts, BBS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,793 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BBS7-associated GO terms across cancer lineages are Centriole-centriole cohesion, Chromosome segregation, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with BBS7 in more than 15 cancer types. Because this analysis shows association rather than direction, both BBS7-to-partner and partner-to-BBS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centriole-centriole cohesion grouped by BBS7-low versus BBS7-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS7→partner) and Y-score (partner→BBS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Centriole-centriole cohesion →	+0.088	+0.607	<.001	.001	3	16
PANCREAS	Chromosome segregation →	+0.077	+0.593	<.001	<.001	3	15
URINARY_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.120	+0.716	<.001	.001	3	14
LUNG_NSCLC_LUSC	Regulation of mitotic metaphase/anaphase transition →	+0.130	+0.877	<.001	.001	3	14
OESOPHAGUS	Regulation of chromosome segregation →	+0.121	+0.635	.004	.001	3	14
BLOOD_Leukemia	Nuclear chromosome segregation →	+0.101	+0.945	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,793 associations by consensus.

Centriole-centriole cohesion by BBS7 expression — STOMACH

Explore this box plot interactively →