BBS5

Across TCGA pan-cancer cohorts, BBS5 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated BBS5 data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher BBS5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated BBS5 expression acts as an unfavorable survival marker.

GBM are the cancer types where BBS5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.288	0.646	.013	4	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

BBS5–GBM (OS)

Open the GBM breakdown →