BBS5

Across TCGA patient cohorts, BBS5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,301 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BBS5-associated proteins across cancer lineages are IFT122, BBS2, and BBS7. Each is linked with BBS5 in more than 6 cancer types. Because this analysis shows association rather than direction, both BBS5-to-partner and partner-to-BBS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBS5 versus IFT122 in UCEC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS5→partner) and Y-score (partner→BBS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IFT122 →	+0.325	+0.423	<.001	<.001	3	7
BRCA	BBS2 →	+0.497	+0.659	<.001	<.001	3	6
UCEC	BBS7 →	+0.368	+0.508	<.001	<.001	3	6
UCEC	TRAF3IP1 →	+0.480	+0.618	<.001	<.001	3	5
UCEC	CFAP36 →	+0.452	+0.578	<.001	<.001	3	5
BRCA	WDR19 →	+0.422	+0.849	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,301 associations by consensus.

BBS5 vs IFT122 — UCEC

Explore this scatter interactively →