BBS10

Across TCGA patient cohorts, BBS10 protein abundance is significantly associated with the RNA expression of many other genes, with 3,250 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BBS10-associated genes across cancer lineages are CFL1P1, NINL, and CBX1. Each is linked with BBS10 in more than 2 cancer types. Because this analysis shows association rather than direction, both BBS10-to-partner and partner-to-BBS10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBS10 versus CFL1P1 in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS10→partner) and Y-score (partner→BBS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CFL1P1 →	+0.626	+0.348	<.001	.004	3	3
BRCA	NINL →	+1.708	+1.491	<.001	<.001	3	2
BRCA	CBX1 →	+1.346	+1.190	.001	<.001	3	2
BRCA	VAT1 →	+1.140	+1.021	.001	.002	3	2
BRCA	DDX55 →	+0.923	+1.291	.007	.002	3	2
BRCA	SUDS3 →	+0.683	+0.932	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,250 associations by consensus.

BBS10 vs CFL1P1 — GBM

Explore this scatter interactively →