BBS10

Across TCGA cell cohorts, BBS10 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BBS10-associated genes across cancer lineages are TAAR2, KRTAP10-7, and OR8B12. Each is linked with BBS10 in more than 1 cancer types. Because this analysis shows association rather than direction, both BBS10-to-partner and partner-to-BBS10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR2 grouped by BBS10-low versus BBS10-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS10→partner) and Y-score (partner→BBS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TAAR2 →	+0.015	+4.285	<.001	.007	3	1
STOMACH	KRTAP10-7 →	+0.020	+4.285	<.001	.007	3	1
OVARY	OR8B12 →	+0.023	+5.807	<.001	.001	3	1
OVARY	OR8B4 →	+0.020	+5.807	<.001	.001	3	1
SKIN	LY6H →	+0.175	+4.095	<.001	.009	3	1
LARGE_INTESTINE	MOGAT1 →	+0.108	+2.878	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TAAR2 by BBS10 expression — STOMACH

Explore this box plot interactively →