BBS1

Across TCGA patient cohorts, BBS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,661 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BBS1-associated proteins across cancer lineages are DHX9, RBBP5, and ILF3. Each is linked with BBS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both BBS1-to-partner and partner-to-BBS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBS1 versus DHX9 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS1→partner) and Y-score (partner→BBS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DHX9 →	+0.207	+0.263	<.001	<.001	3	6
LSCC	RBBP5 →	+0.235	+0.248	<.001	<.001	3	6
GBM	ILF3 →	+0.220	+0.252	<.001	<.001	3	6
GBM	VEZF1 →	+0.406	+0.398	<.001	<.001	3	5
GBM	YTHDC1 →	+0.307	+0.276	<.001	.001	3	5
LSCC	GTF3C4 →	+0.404	+0.374	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,661 associations by consensus.

BBS1 vs DHX9 — GBM

Explore this scatter interactively →