BBS1

Across TCGA cell cohorts, BBS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,457 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BBS1-associated GO terms across cancer lineages are Cilium-dependent cell motility, Cilium movement involved in cell motility, and Cilium or flagellum-dependent cell motility. Each is linked with BBS1 in more than 17 cancer types. Because this analysis shows association rather than direction, both BBS1-to-partner and partner-to-BBS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium-dependent cell motility grouped by BBS1-low versus BBS1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BBS1→partner) and Y-score (partner→BBS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cilium-dependent cell motility →	-0.114	-1.003	<.001	<.001	3	18
LUNG_SCLC	Cilium movement involved in cell motility →	-0.112	-0.940	<.001	<.001	3	18
URINARY_TRACT	Cilium or flagellum-dependent cell motility →	-0.114	-1.003	<.001	<.001	3	18
LUNG_SCLC	Sperm motility →	-0.124	-0.954	<.001	<.001	3	17
LUNG_SCLC	Flagellated sperm motility →	-0.124	-0.954	<.001	<.001	3	17
KIDNEY	Process utilizing autophagic mechanism →	+0.074	+1.165	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,457 associations by consensus.

Cilium-dependent cell motility by BBS1 expression — URINARY_TRACT

Explore this box plot interactively →