BBOX1

Across TCGA patient cohorts, BBOX1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,473 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BBOX1-associated genes across cancer lineages are HMGA1, GSTM3, and VCAM1. Each is linked with BBOX1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BBOX1-to-partner and partner-to-BBOX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BBOX1 versus HMGA1 in PDAC, with a Pearson correlation of -0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BBOX1→partner) and Y-score (partner→BBOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HMGA1 →	-1.243	-2.519	.009	.009	3	5
LSCC	GSTM3 →	-1.916	-0.835	.002	.002	3	4
GBM	VCAM1 →	+1.170	+0.517	<.001	.005	3	4
UCEC	SLC28A3 →	+1.225	+1.307	<.001	<.001	3	4
LSCC	CDKN3 →	-1.026	-0.912	<.001	<.001	3	4
LSCC	DESI2 →	-0.669	-1.329	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,473 associations by consensus.

BBOX1 vs HMGA1 — PDAC

Explore this scatter interactively →