Across TCGA pan-cancer cohorts, BBIP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BBIP1 data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BBIP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated BBIP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

UCEC, HNSC, and LSCC are the cancer types where BBIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	0.386	1.000	.002	28	view →
HNSC	DFS	Median	All	1.000	0.535	.036	11	view →
LSCC	DFS	Quartile	II,III,IV	0.817	1.000	.016	2	view →
LUAD	DFS	Median	All	0.751	0.485	.027	1	view →
PDAC	OS	Median	All	0.958	0.728	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: BBIP1 tumor-vs-normal RNA expression · all BBIP1 data types