Across TCGA patient cohorts, BBIP1 mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BBIP1-associated genes across cancer lineages are FBXW7-AS1, NUDT4P2, and FXNP2. Each is linked with BBIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BBIP1-to-partner and partner-to-BBIP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BBIP1→partner) and Y-score (partner→BBIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FBXW7-AS1 →	+0.360	+3.356	.002	.001	3	1
UCEC	NUDT4P2 →	+0.078	+3.484	<.001	.004	3	1
UCEC	FXNP2 →	+0.243	+3.039	.002	.005	3	1
UCEC	RN7SL134P →	+0.205	+3.277	<.001	.002	3	1
UCEC	SNORA59B →	+0.371	+3.979	<.001	<.001	3	1
UCEC	MIR3135A →	+0.559	+3.131	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

Exploration

BBIP1 survival (RNA) · tumor vs normal (RNA) · all BBIP1 data types