BBC3

Across TCGA cell cohorts, BBC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,941 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BBC3-associated GO terms across cancer lineages are Reduction of food intake in response to dietary excess, GDF15-GFRAL signaling pathway, and Chromosome segregation. Each is linked with BBC3 in more than 16 cancer types. Because this analysis shows association rather than direction, both BBC3-to-partner and partner-to-BBC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Reduction of food intake in response to dietary excess grouped by BBC3-low versus BBC3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BBC3→partner) and Y-score (partner→BBC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Reduction of food intake in response to dietary excess →	+1.511	+1.186	<.001	.002	3	17
BONE	GDF15-GFRAL signaling pathway →	+1.200	+1.092	.001	.006	3	15
OVARY	Chromosome segregation →	-0.066	-1.448	.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of metaphase/anaphase transition of cell cycle →	-0.164	-0.949	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome separation →	-0.164	-0.949	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	-0.071	-0.715	.001	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,941 associations by consensus.

Reduction of food intake in response to dietary excess by BBC3 expression — BONE

Explore this box plot interactively →