BAZ2A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BAZ2A mutation is significantly associated with the RNA expression of many other genes, with 3,572 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAZ2A-associated genes across cancer lineages are RPL23AP72, VPS18, and PRAMEF28P. Each is linked with BAZ2A in more than 2 cancer types. Because this analysis shows association rather than direction, both BAZ2A-to-partner and partner-to-BAZ2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP72 grouped by BAZ2A-low versus BAZ2A-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ2A→partner) and Y-score (partner→BAZ2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SARCRPL23AP72 →+0.122+4.291.002.00733
UCECVPS18 →+0.440+1.628<.001<.00133
GBMPRAMEF28P →+0.037+5.584<.001.00332
UCECARRDC3-AS1 →+0.165+1.321.004.00232
UCECRASSF1-AS1 →+0.429+1.787<.001<.00132
KIRPRNU6-694P →+0.273+4.733<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,572 associations by consensus.

RPL23AP72 by BAZ2A expression — SARC

Box plot of RPL23AP72 in BAZ2A-low vs BAZ2A-high samples in SARC.

Explore this box plot interactively →

Exploration