BAZ2A

Across TCGA patient cohorts, BAZ2A mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAZ2A-associated genes across cancer lineages are TIGAR, mTOR_pS2448, and Caspase-7-cleavedD198. Each is linked with BAZ2A in more than 2 cancer types. Because this analysis shows association rather than direction, both BAZ2A-to-partner and partner-to-BAZ2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIGAR grouped by BAZ2A-low versus BAZ2A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ2A→partner) and Y-score (partner→BAZ2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TIGAR →	+0.111	+2.820	.048	.035	3	3
UCEC	mTOR_pS2448 →	-0.155	-2.117	<.001	<.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.493	+1.678	.005	.019	3	3
UCEC	4E-BP1 →	+0.226	+1.392	.005	.021	3	3
UCEC	ERK2 →	+0.162	+2.222	.004	.009	3	2
UCEC	FoxM1 →	+0.180	+1.807	.019	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

TIGAR by BAZ2A expression — SKCM

Explore this box plot interactively →