BAZ2A

Across TCGA cell cohorts, BAZ2A mutation is significantly associated with the RNA expression of many other genes, with 492 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BAZ2A-associated genes across cancer lineages are TPPP2, ALDH6A1, and NFYB. Each is linked with BAZ2A in more than 1 cancer types. Because this analysis shows association rather than direction, both BAZ2A-to-partner and partner-to-BAZ2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPPP2 grouped by BAZ2A-low versus BAZ2A-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ2A→partner) and Y-score (partner→BAZ2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	TPPP2 →	+0.043	+4.285	<.001	.003	3	2
LARGE_INTESTINE	ALDH6A1 →	+1.207	+3.234	<.001	.004	3	2
LARGE_INTESTINE	NFYB →	+0.549	+3.212	<.001	.006	3	2
BREAST	AURKAIP1 →	+0.532	+3.099	.007	.005	3	2
BREAST	OTUD6A →	+0.023	+2.514	.002	.008	3	2
BREAST	KRTAP5-6 →	+0.115	+3.041	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 492 associations by consensus.

TPPP2 by BAZ2A expression — BLOOD_Myeloma

Explore this box plot interactively →