BAZ1B

Across TCGA patient cohorts, BAZ1B mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAZ1B-associated genes across cancer lineages are MSH2, Rab25, and VHL. Each is linked with BAZ1B in more than 1 cancer types. Because this analysis shows association rather than direction, both BAZ1B-to-partner and partner-to-BAZ1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSH2 grouped by BAZ1B-low versus BAZ1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ1B→partner) and Y-score (partner→BAZ1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH2 →	-0.215	-2.781	.005	.003	3	2
UCEC	Rab25 →	-0.426	-2.502	<.001	.001	3	2
UCEC	VHL →	-0.815	-1.847	<.001	.007	3	2
UCEC	ATM →	-0.660	-2.893	<.001	.001	3	2
UCEC	Bax →	+0.268	+1.874	<.001	.002	3	2
UCEC	Caspase-7-cleavedD198 →	+0.663	+2.321	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MSH2 by BAZ1B expression — UCEC

Explore this box plot interactively →