BAZ1B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BAZ1B mutation is significantly associated with the RNA expression of many other genes, with 157 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BAZ1B-associated genes across cancer lineages are MINAR2, C18orf63, and OOSP4B. Each is linked with BAZ1B in more than 1 cancer types. Because this analysis shows association rather than direction, both BAZ1B-to-partner and partner-to-BAZ1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MINAR2 grouped by BAZ1B-low versus BAZ1B-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ1B→partner) and Y-score (partner→BAZ1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCMINAR2 →+0.042+4.044.007.00931
LUNG_SCLCC18orf63 →+0.012+5.169<.001<.00131
LUNG_SCLCOOSP4B →+0.175+4.643<.001.00431
URINARY_TRACTFABP9 →+0.056+5.087<.001.00431
BLOOD_LymphomaNOBOX →+0.003+4.247<.001.00431
BLOOD_LymphomaMYL10 →+0.118+4.247<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 157 associations by consensus.

MINAR2 by BAZ1B expression — LUNG_SCLC

Box plot of MINAR2 in BAZ1B-low vs BAZ1B-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration